ETHYL 2-OXO-2-(2-THIENYL)ACETATE

ETHYL 2-OXO-2-(2-THIENYL)ACETATE - Names and Identifiers

Name	ETHYL THIOPHENE-2-GLYOXYLATE
Synonyms	Aclidinium Impurity 8 ETHYL 2-THENOYLFORMATE Ethyl-oxo-2-thiopheneacetate ETHYL THIOPHENE-2-GLYOXYLATE Ethyl 2-oxo-2-(thiophen-2-yl) Aclidinium bromide Impurity 8 ETHYL 2-OXO-2-(2-THIENYL)ACETATE 2-THIOPHENE GLYOXYLIC ACID ETHYL ESTER
CAS	4075-58-5
EINECS	223-793-7

ETHYL 2-OXO-2-(2-THIENYL)ACETATE - Physico-chemical Properties

Molecular Formula	C8H8O3S
Molar Mass	184.21
Density	1.25
Boling Point	102-110 °C (0.8 mmHg)
Flash Point	>110°C
Storage Condition	Keep in dark place,Sealed in dry,2-8°C
Refractive Index	1.543-1.549
MDL	MFCD00015538
Use	Application of ethyl 2-thiophenol ethyl acetate can be used as pharmaceutical synthesis intermediates, such as IR absorber, as organic semiconductor in organic devices, these organic devices, in particular organic photovoltaic devices and photodiodes or devices containing diodes and/or organic field-effect transistors, can have excellent solubility in organic solvents and excellent film-forming properties.

ETHYL 2-OXO-2-(2-THIENYL)ACETATE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.

ETHYL 2-OXO-2-(2-THIENYL)ACETATE - Upstream Downstream Industry

Raw Materials

THIOPHEN-2-YL-MAGNESIUM BROMIDE 1.0M
2-Thiopheneglyoxylic acid
(E)-3-DIMETHYLAMINO-1-THIOPHEN-2-YL-PROPENONE
2-THENOYLACETONITRILE
2-(TRIBUTYLSTANNYL)THIOPHENE
Ethyl 2-thiopheneacetate
2-Thiopheneacetonitrile
Ethyl acetate
2-Bromothiophene
Ethanol
Diethyl oxalate
Thiophene(SIV) (9CI)
Ethyl oxalyl monochloride

ETHYL 2-OXO-2-(2-THIENYL)ACETATE - Nature

solubility	Difficult to mix.
BRN	5651

Last Update：2024-04-10 22:29:15

ETHYL 2-OXO-2-(2-THIENYL)ACETATE - Preparation

Suspend 9.77gAlCl3 in 50ml of dichloromethane and then drop 5g of ethyl oxalyl chloride (ethylchlorooxoacetate) at -20°C and nitrogen. Then 6.09 g2-thiophene was added dropwise at -20 ℃ and stirred. After stirring for 1h, the reaction mixture was poured into ice-water and the compound 2-thiophenyl ethyl acetate was extracted using ethyl acetate. The product was purified by column chromatography.

Last Update：2024-04-10 22:29:15